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Methodology The rats were exposed to a light/dark cycle, with standard temperature and humidity levels. The animals were randomly selected to receive chemical injection of the streptozotocin (STZ) to induce diabetes. Those rats that did not receive STZ (vehicle injected) served as controls. The experiments began on each of the rats four weeks after the injections.
Psychological therapy may be effective in conjunction with medical or surgical treatment. Sex therapists emphasize the need for men and their partners to be motivated and willing to adapt to psychological and behavioral modifications, including those that result from medical or surgical treatment.
The physical examination can reveal clues for physical causes of erectile dysfunction. For example, if the penis does not respond as expected to touching, a problem in the nervous system may be the cause. Small testicles, lack of facial hair and enlarged breasts can point to hormonal problems such as hypogonadism with low testosterone levels. A reduced flow of blood as a result of atherosclerosis can sometimes be diagnosed by finding diminished arterial pulses in the legs or listening with a stethoscope for bruits (the sound of blood flowing through narrowed arteries). Unusual characteristics of the penis itself could suggest the root of the erectile dysfunction, for example, bending of the penis during erection could be the result of Peyronie's disease.
Overview and symptoms
The ability to achieve and sustain erections require:
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At least 7 PDE classes are known, many with subtypes identified by structure and function. PDE-5 is cGMP-specific and is a major cGMP-hydrolyzing enzyme in the vascular smooth muscle of the penis. The newer agents, vardenafil and tadalafil, are more specific and potent cGMP inhibitors than sildenafil. Both of the newest agents are PDE-5 inhibitors, which are significantly more selective in their inhibition.
"There is an association, but we don't know which one comes first," said study author Dr. Xiang Gao, an instructor in medicine at Harvard University School of Public Health. If researchers do discover how they're connected, it could lead to more effective treatments, he said.
A few causes of impotence may be iatrogenic (medically caused). Various antihypertensives (medications intended to control high blood pressure) and some drugs that modify central nervous system response may inhibit erection by denying blood supply or by altering nerve activity.
Consult your health care provider to see if one of these treatments is right for you.
Generally, sexual function suffers when you have health problems that damage vascular health and blood flow. So, while Viagra may be a quick fix, it doesn't address the underlying health problems that are plaguing your sex life.
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Reprints: Dr. Setter, Department of Pharmacotherapy, College of Pharmacy, Washington State University/Elder Services, 5125 N. Market St., Spokane, WA 99217-6131, fax 509/458-7459, email@example.com
Erectile dysfunction. The presence of normal skin sensation adequate to produce an erection is measured with this device.
Could ED be a sign of heart disease? Tell your doctor about any heart disease risk factors you may have, such as:
Li said the study is significant because chemical manufacturers and other defenders of BPA have long complained that research raising questions about its health effects was conducted on laboratory animals.
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